Low Dose Naltrexone (LDN) – A Safe, Non-Opiate Pain Relief Alternative5 min read

The following two tabs change content below.
I have been and am close to those whose bodies have manifested autoimmune dis-ease and other maladies considered incurable by any means… and it is they who have inspired my research and writing on health, wellbeing and consciousness for over fifteen years, on my blog and beyond.

Is there a drug which, in low doses may help relieve the pain and inflammation of autoimmune and other disease?… Ever heard of Low Dose Naltrexone [LDN] possibly the only drug that we might call “alternative medicine”?…

I personally know two people some of whose symptoms and suffering from autoimmune have been relieved by low dose naltrexone: one with severe MS and one with scleroderma (systemic sclerosis)… and so I am delighted to pass on to you some promising, hopeful information on LDN that I originally came across in my broader health research on inflammation as the lowest common denominator implicated as the cause or across the board contributing factor to many maladies.

Low Dose Naltrexone Has Helped vs. Autoimmune Inflammation and Pain…
in Treating such as Scleroderma (systemic sclerosis), Lupus and MS and other autoimmune and neurodegenerative diseases including Parkinson’s, as well as various cancers

“Drug” is not always a “4-letter word”: Even Dr.John Bergman, who rarely recommends pharmaceuticals to his patients, is intellectually honest enough to recommend LDN as he is aware of its beneficial effects not only in relieving symptoms such as pain of autoimmune disease, but evidently in going toward healing the bodies of those so afflicted…

No panaceas or magic, “one-shot” cures… especially since each person is different particularly in the case of autoimmune… However, this is worth knowing about and one good starting point to learn about LDN is the user-friendly web site http://lowdosenaltrexone.org/, which has information that is well-researched and annotated and has several Success Stories displayed at the top of its home page, that I went to after watching a YouTube video entitled “Auto Immune Disease 2012” put forth by Dr. Bergman.
How Does LDN Work?… “Harvard educated neurologist New York M.D., Dr. Bernard Bihari discovered that IN VERY LOW LEVELS the drug naltrexone raises endorphin levels and thus modulates or orchestrates the immune system” to relieve pain with no or very minimal side effects, as Julia Schopick explains in this 9-minute video at https://www.youtube.com/watch?v=gcihi0ogHJg

How Did Low Dose Naltrexone Come to be Used?

Jackie Young-Bihari tells the story of Low Dose Naltrexone (LDN) on behalf of her husband Dr Bernard Bihari, LDN pioneer and prescribing Doctor at https://youtu.be/hQk5wg3ilQg
Dr. Bernard Bihari, a man “ahead of his time” who believed in the good, old-fashioned scientific method without any preconceived notions developed LDN [Naltrexone in Low Doses] as an off label use [a use in addition to what a drug was made and approved for] of naltrexone… as he passed through his work with those with addiction (due to substance abuse) and A.I.D.S. [“AI” in “A.I.D.S.” after all stands for Autoimmune]. As he proceeded with his research (including both himself and his wife taking it), he came to understand that while Naltrexone in big pharma doses that were administered… surely did NOT heal OR even help the Immune systems of those with the A.I.D.S. diagnosis… However, naltrexone in LOW DOSES, could…

This article, “What Is the Cost of Low Dose Naltrexone [LDN]?” at https://www.compoundingcenter.com/cost-low-dose-naltrexone-ldn/ ~ states: “Feel free to share… with someone you know who suffers from an autoimmune disorder. Knowing that LDN is quite affordable could make the difference in their treatment,” and so I’m sharing from that article:

“LDN is a non-addictive drug that can be used to treat symptoms of inflammation, immune system problems, and pain caused by Lyme disease and other autoimmune disorders. It is available only by prescription and is custom made at a compounding pharmacy. Naltrexone [NOT low dose] is commercially manufactured in 50mg tablets, but [only] a compounding pharmacy is able to prepare low dose variations, which are needed for treating immune system disorders.”

“Naltrexone was originally marketed to help with opioid addiction. [Note: Opioids are substances used for pain relief, often with considerable “side effects” such as   nausea, itchiness, respiratory issues, depression or constipation] In the late 80s, researchers found that a very low dosage of Naltrexone showed promising results in the treatment of autoimmune disorders.“

Drugs being used for purposes other than what the US FDA approved them for is perfectly legal and is known as “off label” use. LOW DOSE naltrexone is in that category
As “this is not an FDA-approved usage for the drug, “ the article continues, “that means most insurance companies will not cover LDN. But you don’t have to worry about your insurance not covering the medication. It turns out that LDN is an affordable option for patients to use, in addition to their traditional therapy. Low dose naltrexone is prescribed in 1.5 mg to 4.5 mg dosages. Depending upon the dosage prescribed for you, LDN therapy costs about $1 per day. Typically, you will pay less than $100 for a three month’s supply.”

“You may find some websites suggesting that you purchase the more common 50 mg naltrexone tablets and dissolve them in distilled water. However, there are pitfalls to this method. Measuring the correct amount is difficult, especially with household measuring cups and spoons.  Additionally, there is no data to show that naltrexone is stable in water or for how long. It really does not make sense to do this because of the concerns with stability of the liquid, measuring the right amount, and really just the hassle of it. You will not save a significant amount of money given the low cost of LDN capsules.”

Can you cut naltrexone tablets?

“Because LDN must be obtained at a compounding pharmacy, some people try to purchase the regular 50 mg tablets and cut them into smaller portions. The problem is that it is impossible to cut these tablets into an appropriate low dose portion using household instruments. You will end up with crumbs and potentially taking far too much naltrexone for Lyme disease or an autoimmune disorder. In our bodies, this medication [in doses that are NOT LOW] works much differently at higher dosages,” so though we may like “do-it-yourself”… that doesn’t appear like it would be a good idea in this case.

Print Friendly, PDF & Email





I have been and am close to those whose bodies have manifested autoimmune dis-ease and other maladies considered incurable by any means… and it is they who have inspired my research and writing on health, wellbeing and consciousness for over fifteen years, on my blog and beyond.